Flow Chemistry-Asymchem Labs.

Continuous Reaction

As a global CDMO industry pioneer in commercial application of continuous reaction, Asymchem is one of the earliest companies applying continuous manufacturing technology to drug production. Continuous reaction technology can effectively reduce safety risks, reduce environmental pollution, save energy consumption, and solve problems such as unstable product quality, large equipment footprint and difficult process scale up. The continuous reaction business covers fine chemical fields such as pharmaceuticals, pesticides, polymers, synthetic biology and more, providing full process process development, validation and manufacturing services from preclinical to commercial production.

Core Competencies

Specialized expertise in continuous reaction technology since 2008

Over 180 continuous reaction related patents (as of the end of 2024)

Hundreds of tons scale up experience, totaling over 500 continuous projects

Independent continuous reaction equipment design, validation, manufacturing and installation capabilities

Over 300 experienced continuous technology R&D personnel and engineers

Supported Common Reaction Types

Low temperature reactions (-100°C to 20°C)

Photobromination, metal synergistic coupling reactions

High temperature / high pressure reactions (150°C to 300°C)

Electrocatalytic redox, synergistic coupling reactions

Diazomethane reactions

Azidation, Curtius rearrangement reactions

Ozonolysis, oxygen oxidation reactions

Oxidation reactions involving peroxides

Continuous hydrogenation

Gas involved reactions (such as hydrogen, ozone, oxygen, acetylene, ethylene, carbon monoxide, carbon dioxide, ammonia, etc.)

Enzyme catalyzed reactions

Grignard reagent preparation and reactions

Nitration, Sandmeyer reactions

Full process support

Continuous reaction technology applications cover from preclinical to commercial production.

Equipped with process analytical technology (PAT), achieving end to end continuous manufacturing

Scale up guarantee

The workshops strictly follow international quality management system standards, are FDA inspected and certified GMP workshops, with 8,200m² continuous manufacturing area and daily production capacity over 2,000m³.

Capable of continuous process validation and filing, with experience in commercial hundreds of tons scale up.

Sustainability

Improve process performance and safety

Shorten production cycles

Reduce labor costs

Reduce carbon emissions

The world's first company to win the American Chemical Society "CMO Green Chemistry Excellence Award"

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